Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Sapporo (62% of total searches to Hokkaido Prefecture). The next most popular destinations are Niseko (22%) and Hakodate (10%). Searches for hotels in Otaru (6%) are also popular.
KAYAK users have found double rooms in Hokkaido Prefecture for as cheap as $14 (Sapporo) in the last 3 days. The average price is $156.