Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is St. Louis (36% of total searches to Missouri). The next most popular destinations are Kansas City (29%) and Branson (27%). Searches for hotels in Springfield (8%) are also popular.
KAYAK users have found double rooms in Missouri for as cheap as $24 (Kansas City) in the last 3 days. The average price is $178.